RIDOL decreases motility and secretion of intestine and increases the absorption from gut (intestine or bowel).
RIDOL prolongs the transit time of intestinal contents (both small intestinal transit time as well as mouth-to-cecum transit time) and therefore reduces fecal volume,
increases fecal viscosity and bulk density.
RIDOL also diminishes loss of fluid and electrolytes.
The action of RIDOL is prompt and prolonged.
It has a characteristic tissue distribution and almost 85% of the drug can be recovered from the gut, while only 0.04% is present in the brain.
Hence, RIDOL has high anti-diarrhoeal specificity.
RIDOL increases anal sphincter (ring-like muscle which closes a natural passage) tone,
an effect that may be of therapeutic use in some patients who suffer from Anal incontinence (inability to control excretory functions).